hrp0092p1-13 | Adrenals and HPA Axis | ESPE2019

Cytokines and the Impairment of Puberty

Shlyachova Natalia , Turchina Svetlana

The changes of the immune reactivity, the production of hormones and the neuroendocrinal regulation of immune homeostasis are the entities closely connected with the puberty. There is evidence for the role of cytokines in securing of intersystemic interaction as well as for the influence of reproductive hormones on the cytokine production. However, the question as to the role of cytokine in the formation of delayed puberty continues to be relevant.<stron...

hrp0084p3-1228 | Thyroid | ESPE2015

Sex and Age Differences in the Incidence of Thyroid Disease in Children with Obesity

Budreiko Olena , Shushlyapina Olena , Kosovtsova Ganna , Shlyachova Natalia , Nikitina Larisa

Background: Obesity in adults is closely associated with an increased prevalence of thyroid gland (TG) pathology, but thyropathy formation issues among children are not sufficiently studied.Objective and hypotheses: To determine the prevalence and structure of TG pathology in children with obesity by gender and degree of puberty.Method: In 121 patients 6–16 years old with obesity a thyropathy detection was conducted (diffuse n...